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5,7-DHT; 3-(2-Aminoethyl)-1H-indole-5,7-diol
Chemical
C10H12N2O2 . HBr
192.2 . 80.9
31363-74-3 (free base)
Synthetic
≥95% (HPLC)
Grey-brown powder.
Soluble in water.
Determined by NMR.
Manufactured by Chemodex.
Click here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.
KVRZGCBQKAJSBN-UHFFFAOYSA-N
AMBIENT
+4°C
-20°C
Keep cool and dry.Protect from light and moisture.
Stable for at least 2 years after receipt when stored at -20°C.
No
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Autofluorescent serotonin derivative. Serotonergic neurotoxin, depleting serotonin and norepinephrine. Can be used for the identification of living serotonergic neurons even in the presence of dopaminergic neurons. Its selectively uptaken into 5-hydroxytryptamine neurons. It’s oxidation products are often more potent then the parent product.Product References(1) H.G. Baumgarten, et al.; Acta Physiol. Scand. Suppl. 391, 1 (1973) | (2) B. Allis & G. Cohen; Eur. J. Pharmacol. 43, 269 (1977) | (3) K. Fuxe, et al.; Ann. N. Y. Acad. Sci. 305, 346 (1978) | (4) M.Z. Wrona, et al.; J. Med. Chem. 29, 499 (1986) | (5) A.K. Sinhababu & R.T. Borchardt; Neurochem. Int. 12, 273 (1988) | (6) K.T. Finnegan, et al.; Brain. Res. 496, 251 (1989) | (7) H. Franke,et al.; Naunyn Schmiedebergs Arch. Pharmacol. 366, 315 (2002)